Cholinergic Receptors in Cognitive Disorders
نویسندگان
چکیده
منابع مشابه
Cholinergic mechanisms in affective disorders.
Advances in clinical and basic research methodology combined with clearly articulated concepts create new opportunities for researching the roles of cholinergic mechanisms in the pathophysiology of affective disorders. Areas for study include: 1) roles of cholinergic mechanisms in mediating effects of stress and cholinergic mechanisms linking the pathophysiologies of affective and panic disorde...
متن کاملCharacterization of nicotinic cholinergic receptors
Objective: To characterize nicotinic cholinergic receptors (cholinoceptors) in frog rectus abdominis and mouse esophagus. Material and Methods: Isolated preparations of mouse esophagus and frog rectus abdominis were separately mounted in organ baths filled with Krebs and Ringer solutions respectively. The organ bath medium was continuously gassed with 95% O 2 and 5% CO 2 and the temperature was...
متن کاملBehavioral/Systems/Cognitive 4* Nicotinic Receptors in preBötzinger Complex Mediate Cholinergic/Nicotinic Modulation of Respiratory Rhythm
Acetylcholine and nicotine can modulate respiratory patterns by acting on nicotinic acetylcholine receptors (nAChRs) in the preBötzinger complex (preBötC). To further explore the molecular composition of these nAChRs, we studied a knock-in mouse strain with a leucine-to-alanine mutation in the M2 pore-lining region (L9 A) of the nAChR 4 subunit; this mutation renders 4-containing receptors hype...
متن کاملThe rabbit cornea lacks cholinergic receptors.
Cholinergic receptors were studied in membranes prepared from rabbit cornea, iris-ciliary body, and retina, using 3H-quinuclidinyl benzilate (3H-QNB) to identify muscarinic receptors and 125I-alpha-bungarotoxin (125I-BGT) to identify nicotinic receptors. Muscarinic cholinergic receptors were not found in the cornea. As a positive control, muscarinic cholinergic receptors were characterized in p...
متن کاملEffect of gallamine on cholinergic receptors.
EVER SINCE the introduction of gallamine triethiodide (FlaxedilV) into clinical anaesthesia in 1948 by Huguenard and Bou6,1 there have been numerous reports of sinus tachycardia as a side effect. 2-4 Gallamine was found to have a vagolytic action localized in the heart, and for a long time it was presumed that dais was the cause of the tachycardia. 5 Recently, however, Brown and Crout ~ and Smi...
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ژورنال
عنوان ژورنال: Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques
سال: 1986
ISSN: 0317-1671,2057-0155
DOI: 10.1017/s0317167100037240